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Japan Study Influence of overnight orthokeratology on axial length elongation in childhood myopia

This Japanese study compared 92 short-sighted children with an average age of 12 and an average prescription of -2.50D who were divided into two groups - one undertaking Overnight Vision Correction (OVC) treatment and the other wearing spectacles - in terms of how their short-sightedness had developed over a two year period following commencement of treatment. After two years, it was evident that the group wearing overnight ortho-k corrective contact lenses had experienced significantly less elongation of their eyes - which determines focusing distance - than the group wearing spectacles thus demonstrating that the development of their short-sightedness had been slowed down.

January 6, 2011 The Association for Research in Vision and Ophthalmology Tetsuhiko Kakita, MD, Takahiro Hiraoka, MD, Tetsuro Oshika, MD, Kakita Eye Clinic, Chiba, Japan Department of Ophthalmology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan

ABSTRACT

Purpose: This prospective study was conducted to assess the influence of overnight orthokeratology (OK) on axial length elongation in children, with those wearing spectacles as controls.

METHODS: One hundred five subjects (210 eyes) were enrolled in this study. The OK group comprised 45 patients (90 eyes, age 12.1 ± 2.5 years, mean ± SD) (OK group) who matched the inclusion criteria for OK. The control group comprised 60 patients (120 eyes, 11.9 ± 2.0 years) who also matched the inclusion criteria for OK but preferred spectacles for myopia correction. Axial length was measured at baseline and after 2 years using the IOLMaster (Zeiss Humphrey System, CA, USA) and the changes were evaluated and compared between the groups.

RESULTS: Ninety two subjects (42 and 50 in the OK and control groups, respectively) completed the 2-year follow-up examinations. At baseline, the spherical equivalent refractive error was -2.55 ± 1.82 D and -2.59 ± 1.66 D, and the axial length was 24.66 ± 1.11 mm and 24.79 ± 0.80 mm in the OK and control groups, respectively, with no significant differences between the groups. The increase in axial length during the 2-year study period was 0.39 ± 0.27 mm and 0.61 ± 0.24 mm, respectively, and the difference was significant (P < 0.0001, unpaired t test).

CONCLUSIONS: Orthokeratology suppressed axial elongation in myopic children, suggesting that this treatment can slow the progression of myopia to a certain extent.

Read full article: Investigative Opthamology and Visual Science

 

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